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How semaglutide works

Last updated on Mar 30, 2026

Semaglutide is a GLP-1 receptor agonist. It mimics the GLP-1 hormone, which is released naturally after eating, to:

  • Reduce appetite and food intake
  • Slow the rate at which your stomach empties
  • Help regulate blood sugar levels

Wegovy is administered as a once-weekly subcutaneous injection. As with Mounjaro, it is most effective as part of a comprehensive programme that includes lifestyle adjustments.